Cypress Creek is a major tributary of the Pagan River located in Isle of Wight County, Virginia. The tidal waterway flows northward from where it rises from the forested swamps of Great Springs road before merging with the Pagan River near the town of Smithfield. Salt marshes surrounding the creek provide natural habitat for abundant wide life including the great blue heron, egrets, osprey, belted kingfisher and many other bird species.